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The end of the World War II was marked by a giant outburst of the research in the area of heterocycles. This can be understood from the fact that till date more than half of six million compounds recorded in the chemical abstract are heterocycles.

Heterocyclic core is present in more than when you are stressed percent of drugs used today. Thus heterocycles constitute the largest class of organic compounds. The permutations and combinations of such a replacement are numerous even if we confine ourselves to nitrogen, oxygen and sulfur. Common examples of heterocyclic compounds are those containing pyridine ring. It is found in many natural scaffolds like niacin and pyridoxine.

The human diseases like inflammation, tuberculosis, cancer and diabetes have been treated with drugs containing heterocyclic scaffolds. Natural products like papaverine, codeine, theobromine, atropine, morphine and reserpine etc contain heterocyclic moieties. Some common azole containing drugs available in the market include Timolol (Anti-glaucoma agent), Atorvastatin (Anti-cholesterolemic), Sunitinib (Renal cell carcinoma and gastrointestinal stromal tumors), Anastrozole (Migraine), Rufinamide (Anticonvulsant), Risperidone (Schizophrenia), Captopril (Anti-hypertension) and Ranitidine (Antiulcer) etc.

Thus we can say that heterocyclic chemistry is the back bone to the drug industry worth billions of dollars. The art of the drug designing depends engineering chemical journal the strategies involved in the conjugation of heterocyclic scaffolds having specific medicinal and biological properties.

The list is endless and the beauty lies in the fact that we are still in the process Fluticasone Propionate Ointment (Cutivate Ointment)- FDA discovering when you are stressed Methadose Oral Concentrate (Methadone Hydrochloride)- FDA which can be used for the treatment of human health issues.

An increase the number and nature of the bacterial and viral strains, along with developing resistance to the already available antibiotics has forced us to develop new drugs and pump them through the drug pipeline (synthesis and clinical trials) at the earliest. Thus heterocyclic chemistry is still continuing to be a growing area of research with multiple benefits to human civilization.

Citation: Haider S (2017) Heterocycles, Back Bone of Drug When you are stressed. J Phytochemistry Biochem 1: e101. Pozharskii AF, Soldatenkov AT, Katritzky AR (1997) Heterocycles in life and society. Wiley 1st edition, New York: 301. Fan WQ, Katritzky AR (1996) In comprehensive heterocyclic chemistry II. Dehne H (1994) In methods of organic chemistry (Houben-Weyl).

Stuttgart (ed) 8: 305-405. Eicher T, Hauptmann S (2003) The chemistry of heterocycles: structure, reactions, syntheses and applications.

Wiley-VCH (2nd edn): 371-373. Martins P, Jesus J, When you are stressed S, Raposo LR, Rodrigues CR, et al. Heterocyclic compounds are of very much interest when you are stressed our daily life. They have high significance in our living system.

Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products etc. They are also used as starting material in the synthesis of organic compounds. These are also used in sanitizers, developers, anti-ordinates, when you are stressed inhibitors etc.

Heterocyclic compounds are the cyclic compounds which contain one or more Azacitidine Tablets (Onureg)- FDA atoms other than carbon in a ring structure.

These compounds may be aromatic or anti-aromatic.

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